How to handle security on report server?

Reporting Services provides an authentication subsystem and role-based authorization model. Authentication and authorization models vary depending on whether the report server runs in native mode or SharePoint mode. If the report server is part of a SharePoint deployment, SharePoint permissions determine who has access to the report server.
Default authentication is based on Windows Authentication and integrated security. You can change the authentication settings to allow the report server to respond to different authentication requests, or even replace the default security features with a custom authentication extension that you provide.
Authorization is based on roles that you assign to a principle. Each role consists of a set of related tasks, which are in turn composed of related operations. For example, the Manage reports task grants access to the following report server operations: view reports, add report, update report, delete report, schedule report, and update report properties.

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